NEW STEP BY STEP MAP FOR PKRRATING

The interfacial residues are very conserved amongst eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements exhibit the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations aid a design where by activating RNA serves as being a scaffold to bind several PKR monomers, increasing the ne

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